Jordi | Journal of Oral Diagnosis Online Submission Review an Article SOBEP - Sociedade Brasileira de Estomatologia e Patologia Oral
Current Number: V4 - 2019

Case Report

Solitary keratoacanthoma of the lip vermilion: case report and comprehensive review of literature

Aneliza de Fatima Moraes da Silva1; José Humberto Damante2; Luiz Antônio Assis Taveira3; Kellen Cristine Tjioe4

Abstract Download

Solitary keratoacanthoma (S-KA) is a benign epithelial proliferation that affects the sun-exposed skin of elderly. It presents rapid growth often followed by spontaneous remission. S-KA clinical and microscopic features are very similar to the squamous cell carcinoma’s (SCC) and differentiating them can be a challenge. S-KA involving the lip is rare and frequently is managed as SCC, leading to overtreatment. Despite of few investigations aiming at differentiate S-KA and SCC are available, there is no compilation of case reports of lip S-KA. Thus, our aim was to conduct a comprehensive review of the literature and report a case of lip S-KA. The review was conducted until 2016 and only 21 cases were found. Lip S-KA was more common in elder man, lower lip, and most of them were asymptomatic. The lesions measured 16.7mm on average with duration of approximately 12 weeks. The most performed treatment was excisional biopsy of lesion despite of the self-healing potential of the lesion.

Keywords: Keratoacanthoma; Carcinoma, Squamous Cell; Lip; Neoplasm Regression, Spontaneous.

A rare case of enamel pearl in canine tooth

Ana Carolina Ramos Mariz1; Gabriela Meyge de Brito2; Daniela Adorno Farias3; André Wilson Machado2; Paulo Sérgio Flores Campos1

Abstract Download

The enamel pearl (EP) is a dental developmental anomaly that usually manifests in furcation areas, and is uncommon in uniradicular teeth. We present a case of EP on the vestibular surface of tooth 13 in a 38-year-old patient, who was submitted to multislice computed tomography (MSCT) for orthognathic surgery planning. The attenuation coefficient (3.070 HU) allowed the condition to be classified as a true EP.

Keywords: Tooth Abnormalities; Multidetector Computed Tomography; Tooth, Impacted.

Von Recklinghausen disease/type I neurofibromatosis and its association with orofacial changes: Literature review and case report

Monah Sampaio Santos1; Wladimir Gushiken de- Campos2; Camilla Vieira Esteves2; Camila Eduarda Zambon1; André Caroli Rocha1; Gustavo Grothe Machado1; Celso Augusto Lemos2

Abstract Download

Neurofibromatosis is an autosomal dominant genetic disorder and an inherited condition. This pathology represents 90% of the cases found in the general population. Oral manifestations of neurofibromatosis type I can occur in 70 to 92% of cases, especially when a detailed clinical examination is performed associated with complementary imaging tests. Because of this, it is not uncommon for the dental surgeon to be the first health professional to perform the diagnosis of the disease. The importance of having an early diagnosis correlates with the possible complications of the disease. The carrier may have offspring that manifest the disease in its severe form because of the large capacity for variation, which can be avoided with prior genetic counseling. In this study we report a case of a woman diagnosed and treated for central giant cell lesion 44 years ago, with dental, spine and mandible alterations, also with a family history of neurofibromatosis.

Keywords: Neurofibromatosis 1; Maxilla; Mandible; Oral Manifestations..

Botryoid odontogenic cyst: Report of case found in routine imaginological examinations and an update of the literature

John Lennon Silva Cunha1; Amanda Feitoza da Silva2; Joao Vitor Rocha Silva1; Juliana Batista Melo da Fonte3; Bruno Torres Bezerra2; Sílvia Ferreira de Sousa4; Ricardo Luiz Cavalcanti de Albuquerque-Júnior1

Abstract Download

Botryoid odontogenic cyst (BOC) is a rare variant of the lateral periodontal cyst (LPC). As the biological behavior of BOC is variable and the literature is limited to that of individual case reports, there is no accepted consensus on the best management strategy. A 43-year-old Caucasian male was referred to a private dental clinic for routine radiographic examination. Extraoral and intraoral evaluations revealed no alterations. Panoramic radiography, periapical radiography, and cone beam computed tomography revealed a well-circumscribed osteolytic lesion of 2.0 cm in diameter, extending from the region of teeth 33 to 35. The provisional diagnostic was odontogenic keratocyst or lateral periodontal cyst. Histological analysis of the incisional biopsy revealed multiple cystic cavities lined by a thin nonkeratinized epithelium, exhibiting focal plaque-like thickenings, surrounded by a dense fibrous capsule. The diagnosis was BOC. The purpose of this study was to critically analyze the clinical and radiologic features of BOC based on case reports and case series published in the literature from 1973 to 2018 and to add a new one from our files.

Keywords: Bone Diseases; Odontogenic Cysts; Mandible..

Gorham stout syndrome in maxilla and femur

Jaqueline Colaço1; Henrique Cesca1; Gisele Rovani2; Mateus Ericson Flores3; Ferdinando De Conto4

Abstract Download

Gorham Stout syndrome (SGS) is a rare disease that affects the bones causing idiopathic osteolysis. The prognosis of SGS is quite variable and impossible to predict, in most cases, bone destruction progresses from months to years, the affected area does not regenerate or repair itself. The etiology of the disease is unknown. The aim of the present study is to report a case in female patient showing a lesion in the left jaw compatible with the SGS. A 45-year-old female patient, was referred to the CTBMF team. After performing imaging tests to perform the differential diagnosis, they suggested as differential diagnosis of maxillary ossifying fibroma lesion and fibrous dysplasia, in relation to femoral lesion, was suggestive and enchondroma. The proposed treatment was surgical removal with curettage of the lesion in the femur and maxilla. With the result of the histopathological examination, the diagnosis of SGS was concluded. During the postoperative follow-up period, the lesion showed no signs of relapse, guaranteeing success in the treatment.

Keywords: Osteolysis; Maxilla; Neoplasms; Diagnosis..

Labial osteolipoma, clinical and surgical management of an infrequent disease

Ignacio Panico1; Gerardo Marcelo Gilligan2; Liliana Gelman3; René Luis Panico4

Abstract Download

Lipomas are relatively infrequent benign neoplasms of connective tissue that can involve oral mucosa. Different histological subtypes of oral lipomas were previously described in current literature. The aim of this work is to report a clinical case of an 83-year-old male, who presented with a 20-years-old labial mass. Surgical removal was performed, and the histopathological diagnosis reported an oral Osteolipoma (OL). Discussion: There are previous reports of oral lipomas that have histologically presented a combination with other cell lines such as bone and cartilaginous tissue within the tumor. The rarity of its presentation makes this entity an infrequent diagnosis for clinicians and specialists in Oral Medicine. The provisional diagnosis could be aided with X-ray when the mass exam revealed indurated areas and calcifications. There are few cases described of OL in this oral subsite. Because of its unusual presentation, OL of the oral mucosa is a true challenge in oral diagnosis.

Keywords: Lipoma. Soft Tissue Neoplasms. Surgical Procedures, Operative. Diagnosis, Differential.

Calcifying odontogenic cyst treated by a two-stage surgical approach and reconstructed with L-PRF membrane associated to lyophilized bovine bone graft

Juliana Portes1; Karin Soares Gonçalves Cunha1; Bianca Bravim2; Sérgio Gonçalves2; Marina Urquiza3; Danielle Castex Conde1

Abstract Download

Calcifying odontogenic cyst is an uncommon oral lesion, accounting for less than 1% of all odontogenic cysts. We report a case of a 28-year-old female with a complaint of a painless swelling on the anterior mandible area. Panoramic radiography and computed tomography showed a well-defined unilocular radiolucency with a radiopaque focal area, extending from the apical region of teeth 34 to 43. An incisional biopsy showed a cystic lesion lined by ameloblastoma-like epithelium with the presence of ghost cells and calcifying material consistent with the diagnosis of calcifying odontogenic cyst. The treatment of choice was decompression with posterior enucleation of the lesion, and the region was filled-up with L-PRF membrane (Leukocyte - Platelet Rich Fibrin) and lyophilized bovine bone graft (Bio-Oss®). A two-stage treatment starting with decompression allows the prevention of some complications, such as fracture of the jaw or injury of noble structures and consequently, decreases the chances of recurrence. To the best of our knowledge, there are few published cases of COC treated by decompression followed by enucleation. The patient remains on follow-up and after 14 months, there is no sign of recurrence.

Keywords: Calcifying odontogenic cyst; Decompression; Bone regeneration.

Mucosa-associated lymphoid tissue lymphoma in labial minor salivary glands - case report and literature review

Marina Kimie Oba1; Leandro Dorigan de-Macedo1; Ana Carolina Fragoso Motta2; Hilton Marcos Alves Ricz3; Luiz Carlos Conti de-Freitas3; Fabiano Pinto Saggioro4; Lara Maria Alencar Ramos Innocentini1

Abstract Download

Mucosa-associated lymphatic tissue (MALT) lymphomas commonly occur in the stomach however, rare cases of MALT lymphomas involve the minor salivary gland. We did a literature review and described the fourth case in the English literature of adults affected by a MALT lymphoma in the lip. A 68-year-old woman with probable primary Sjögren's syndrome (SS) was referred to our dentistry and stomatology service, complaining that her lower lip had progressively thickened during the past 4 years. An incisional biopsy was performed, and the microscopic examination showed a dense, diffuse lymphoplasmacytic infiltration of the salivary glands, with plasmacytic differentiation. The immunohistochemical analysis revealed diffuse positivity of the neoplastic cells for CD20 and BCL-2; the plasma cells were positive for CD138 and Lambda, which was consistent with MALT lymphoma. SS and Immunoglobulin G4-related disease were excluded. The total regression of the lesion was obtained after treatment with surgery, chemotherapy, and radiotherapy.

Keywords: Minor Salivary Glands; Marginal Lymphoma B-Cell; Treatment Outcome.

Tongue mucocele and microlith associated with a phlebolith mimicking a hemangioma: A unique case report with its surgical management

Nyer Firdoose C.S

Abstract Download

Unique variants of oral mucocele such as the mucocele appearing on tongue are considered to be extremely rare. It is important to recognize these unique variants promptly to avoid misdiagnosis. The cases of phleboliths not associated with vascular lesions are also rarely reported in the literature, especially as solitary nodules. Conclusion: The following manuscript thereby attempts to present a unique case of a geriatric patient with a combination of Tongue mucocele with microlith mimicking a hemangioma associated with phlebolith along with its diagnosis, clinical presentation and surgical management.

Keywords: Hemangioma; Mucocele; Tongue..

Original Article

Unusual bone-forming lesion affecting complete denture wearer: two case reports

Luciana Yamamoto Almeida1; Ana Terezinha Marques Mesquita2; Cássio Roberto Rocha dos Santos2; Alfredo Ribeiro-Silva3; Lana Kei Yamamoto Almeida4; Jorge Esquiche León5

Abstract Download

INTRODUCTION: The use of complete removable dentures is associated with a high frequency of oral mucosal lesions. Among them, denture-induced fibrous inflammatory hyperplasia is one of the most common. Interestingly, some oral lesions occurring beneath complete dentures can present exuberant new bone formation, creating diagnostic difficulties. PATIENTS: We present two interesting cases affecting complete denture wearers, showing each one unusual bone-forming lesion. The first was diagnosed as extensive mature bone formation with osteochondromatous metaplasia foci and the second as an exuberant exostosis. DISCUSSION: Oral soft tissue lesions caused by ill-fitting dentures may present distinct microscopic variations such as osseous and chondromatous metaplasia arising of the connective tissue. These cases evidence that contributing factors for exostosis may be the chronic oral mucosa irritation at the tissue/denture base interface and a response to stresses transferred to the alveolar bone by the ill-fitting denture. CONCLUSION: Awareness of these lesions is essential to avoid unnecessary procedures, prevent misdiagnosis, reduce patient anxiety, consequently influencing oral health related-quality of life of edentulous patients.

Keywords: Exostoses, Osteochondroma, Metaplasia, Denture, Complete.

Clinicopathological parameters of oral squamous cell carcinoma in Florianópolis: A 10-year study

Georgia Martini1; Gustavo de-Los-Santos2; Natalia Bordignon1; Carla Girardi3; Fernanda Viviane Mariano4; Filipe Ivan Daniel1; Rogério Oliveira Gondak1

Abstract Download

Oral squamous cell carcinoma (OSCC) is one of the most common cancers and presents the highest mortality rate of head and neck tumours. The aim of this study was to evaluate the clinical and histological features of patients with OSCC in Florianópolis, Santa Catarina, Brazil between 2006 and 2016. Demographic and clinical characteristics such as age, gender, tobacco and alcohol consumption, anatomical site, clinical stage, and treatment were retrospectively collected from histopathological and medical reports. Of 196 patients with OSCC, 82.14% were male with a mean age of 58.28±10.45 years. Tobacco and alcohol consumption was reported in 88.76% and 75.9% of patients, respectively. The tongue was the anatomical site most affected (25.13%) and ulcers were the most prevalent clinical aspect (95.21%). A total of 103 (52.55%) patients were diagnosed with advanced stage (III/IV). Regarding treatment, 59.24% received more than one type of therapy, while 39.67% were treated exclusively with surgery. Regarding histological differentiation, 72.9% of the cases were moderately/poorly differentiated, 23.8% had vascular invasion, 17.9% had lymphatic invasion, and perineural invasion was observed in 29.5% of the patients. The survival rate showed a worse prognosis for patients diagnosed at stage III/IV and the primary tumour was located in the inferior level of the mouth in 80% of these cases. The results showed that the majority of cases were diagnosed at an advanced stage, compromising treatment and prognosis. Educational and preventive measures should be improved in an effort to allow for early diagnosis.

Keywords: Carcinoma, Squamous Cell; Head and Neck Neoplasms; Ulcer; Tongue..

Giant cell lesion and traumatic bone cyst: pathologically related lesions?

Bianca de Bem Prunes; Natália Batista Daroit; Júlia Silveira Nunes; Joao Júlio da Cunha Filho; Pantelis Varvaki Rados; Fernanda Visioli

Abstract Download

INTRODUCTION: Synchronous lesions of the jaws are reported in the literature and the etiopathogenesis can be similar in some cases. The oral surgeon must know the diseases that may occur simultaneously. OBJECTIVE: The aim of this study was to report a case of synchronous lesions, your management, additionally discuss the etiopathogenesis correlation among these lesions and the possible evolution from one disease to the other in order to aid the professional about the management of this occurrence. METHODS: This study reported a case of a 14-year-old female patient presenting a reddish sessile nodule in mandibular left premolars gingival region. RESULTS: Radiographically, a well-defined radiolucent area involving left mandibular body was observed. An incisional biopsy of the extra-osseous lesion was performed and a giant cell lesion was histopathologically diagnosed. A surgical bone exploratory procedure revealed an empty cavity; therefore curettage to stimulate bleeding was performed in addition to the extra-osseous lesion excision. The final diagnosis was synergistic peripheral giant cell lesion and traumatic bone cyst. The 12 months follow-up did not show any relapse, moreover, the complete bone neoformation was observed. CONCLUSIONS: The pathogenesis of both lesions remains uncertain and a complete and detailed clinical and histopathological examination added to rigorous follow up with image exams resulted in a correct diagnosis and good prognosis of this case.

Keywords: Peripheral Giant Cell Granuloma; Bone Cysts; Jaw Cysts; Jaw Cysts/Etiology..

Dermoid and epidermoid cysts of the mouth: Clinicopathological and cytokeratin profile

Osvaldo Schitini Schitini-Junior1; Aguida Cristina Gomes Henriques1; Valéria Souza Freitas2; Clarissa Araújo Gurgel1; Patrícia Ramos Cury1; Lélia Batista Souza3; Eliabe Almeida dos Santos1; Roberto Almeida De Azevedo1; Viviane Palmeira da Silva1; Jean Nunes dos Santos1

Abstract Download

INTRODUCTION: The mechanisms of cell differentiation and pathogenesis in oral epidermoid cysts and dermoid cyst is poorly know. OBJECTIVE: To report clinicopathological features and investigate cytokeratin profile of oral epidermoid cysts and dermoid cyst. MATERIAL AND METHODS: Eight cases of epidermoid cysts, 4 of dermoid cyst, and 2 Fordyce granules were included. For analysis of the immunohistochemical expression of cytokeratins (6, 7, 8, 10, 13, 14, 18 and 19), brown staining in the sections examined were defined as positive considering three layers: superficial, intermediate and basal. RESULTS: In dermoid cyst, cytokeratins 7, 8, 9 and 19 were expressed in one case. Cytokeratin 6 was detected in six cases of epidermoid cysts. Cytokeratins 10, 13 and 14 were expressed in all cysts. Cytokeratin 18 was absent in all cysts. Cytokeratins 10 and 14 was observed in Fordyce granules. Cytokeratin 10 was more expressed in peripheral cells and immature sebaceous glands. As these glands became more differentiated, cytokeratin 10 was not detected, while cytokeratin 14 was expressed in mature sebocytes. Cytokeratins 10, 13 and 14 were expressed in the lining mucosa adjacent to Fordyce granules, similar to normal oral mucosal lining. CONCLUSION: cytokeratin profile is altered in dermoid cyst and epidermoid cysts compared to lining oral mucosa.

Keywords: Dermoid Cyst; Epidermal Cyst; Keratins..

Interrelation study between drugs and oral lesion development in patients with special needs

Briana Góes Monteiro1; Maria Cecília Fonsêca Azoubel2; Juliana Borges de Lima Dantas3; Alena Ribeiro Alves Peixoto Medrado4

Abstract Download

INTRODUCTION: Special dentistry is an area that of dentistry that concerns itself with treating patients with special needs. To greater knowledge of the specific special needs by the dentist, there is an urgent need to emphasize the importance of proper odontologic treatment, whether in office or in a hospital environment to this population OBJECTIVES: The aim of this study was to correlate the use of drugs in patients with special needs with the development of oral lesions and to better characterize this population. MATERIALS AND METHODS: This was a quantitative and qualitative cross-sectional study which included special needs patients from the Brazil's Universal Health-Care System. Analysis of medical records and intraoral physical examination was performed for 88 patients and descriptive data was extracted. RESULTS: The patient population was predominantly female (54.5%) and older than 18 years of age (62.5%). A higher frequency of neurological and psychomotor disorders (54.5%), hypertension (29.5%) and diabetes mellitus (15.9%) was found. A total of 21.6% patients reported a"dry mouth." sensation. The drugs most frequently used were anticonvulsants (46.5%), anxiolytics (35.2%) and anti-hypertensives (34%). The highest percentage of lesions corresponded to gingival enlargement (19.3%), followed by gingivitis (10.2%) and candidiasis (7.9%). CONCLUSION: It is expected that results derived from this research can contribute to a better understanding of the interrelationship between the use of pharmaceutical agents and the appearance of lesions in the oral mucosa, as well as to indirectly improve oral health of certain patient populations.

Keywords: Disabled Persons; Pathology, Oral; Pharmacology; Mouth Mucosa; Metabolic Side Effects of Drugs and Substances..

Crohn's disease: Low-Level Laser Therapy (LLLT) as an adjuvant treatment of oral lesions

Cíntia de Souza Alferes Araújo1; Carolina Eurich Mazur2; Vitória Maria de-Melo Nardino1; Hanagleicy Souza1; Roberta Targa Stramandinoli-Zanicotti2; Mirella Lindoso Gomes Campos3; Edimar Rafael Oliveira2; José Miguel Amenábar2

Abstract Download

Classified as a chronic inflammatory bowel disease, Crohns disease (CD) has a multifactorial etiology. Individual with CD can present signs/symptoms such as abdominal pain, fever, diarrhea with a serious risk of hemorrhagic progression, weight loss, anemia and malnutrition. Extra-intestinal complications of CD such as at mouth are probable in some cases. In the mouth, it may presents ulcers, verrucous lesions, swelling of the lips, recurrent aphthous stomatitis, and predisposition to fungal, bacterial and viral infections. In view of the patient's clinical condition, oral manifestations variable, painful symptomatology and challenge in the choice of oral lesions treatment, this study presents a case of Chron's Disease's oral manifestations and its management with Low-Level Laser Therapy (LLLT).

Keywords: Crohn Disease, Mouth, Laser Therapy.

Clinicopathological study of sialolithiasis: a retrospective analysis of 11 cases

Isabele Cardoso Vieira De-Castro1; Angelo Adalberto Ferreira de-Jesus2; Roberto Almeida De Azevedo3; Paulo Sérgio Flores Campos4; Jean Nunes dos Santos5

Abstract Download

Sialolithiasis is one of the most common benign conditions that affect the salivary glands. The disease is characterized by obstruction of the gland parenchyma or ductal system that reduces the salivary flow rate. Most sialoliths occur in the major salivary glands and usually cause acute and chronic infections. Since an inaccurate clinical diagnosis of sialolithiasis is often reported, the aim of this study was to describe the clinical and histopathological features of 11 cases of sialolithiasis over a period of 13 years retrieved from the Oral Pathology Service of the Federal University of Bahia, Brazil. Most sialolithiasis cases involved the major salivary glands and were identified between the 4th and 5th decade of life. There was a slight female predominance. The lesions were usually symptomatic and appeared as a single nodule of firm consistency. The most common location was the submandibular gland, followed by the minor salivary glands (oral mucosa). Surgical excision was performed in all cases. Histopathology revealed a lamellar pattern of calcification of the sialoliths, chronic inflammation, and ductal squamous metaplasia.

Keywords: Salivary gland calculi, Submandibular gland, Pathology, Diagnosis.

Foreign-body reaction to an alveolar dressing (Alvogyl®): Presentation of 4 cases

Didac Sotorra-Figuerola; Javier Alberdi-Navarro; Maria-Luisa Gainza-Cirauqui; Juan Pablo Muñoz-Zapata; Jose-Manuel Aguirre-Urizar


Keywords: .

Sclerotherapy in oral cavity hemangioma with glucose and ethanolamine oleate. Case reports

Marcio Goncalves da-Silva; Michelle Palmieri; Henrique Camargo Bauer; Anna C R T Horliana; Waldyr Antonio Jorge; Renata Matalon Negreiros


Keywords: .

Compound odontoma associated to permanent teeth impaction in jaw: case report

Daniela Meneses-Santos1; Andre Silva Góis2; Klinger de Souza Amorim3; Ricardo Luiz Cavalcanti Albuquerque Junior4; Liane Maciel de Almeida Souza1

Abstract Download

The odontoma is a benign tumor of odontogenic origin, is considered a developmental malformation (hamartoma). The compound odontoma is formed by all tissues of a normal tooth arranged in an organized manner. Odontomas have slow growth and are not aggressive; most are asymptomatic, being diagnosed in routine radiographs. This study aims to present a case report of compound odontoma associated with impaction of permanent teeth in the jaw. Treatment opted for the surgical removal of the compound odontoma and permanent impacted teeth.

Keywords: Compound Odontoma; Impacted Teeth; Tooth Eruption; Mandible..

Epidemiologic study of patients attended in an Oral Medicine Service between 2014-2016

Thayanne Brasil Barbosa Calcia1,2; Sarah Aparecida Ferreira Antero2; Wagner Pinto das-Chagas2; Nathalia de Almeida Freire2; Mônica Simões Israel2; Rosemiro de Menezes Maciel2

Abstract Download

Oral medicine is a dental specialty intended to diagnose current oral diseases, as well as to diagnose and prevent oral manifestations of systemic diseases. This study aimed to evaluate the most commonly diagnosed lesions, as well the main epidemiological characteristics of the patients attended at the oral medicine clinic of São Leopoldo Mandic School - Rio de Janeiro in the period between 2014 and 2016. At the end of the study, a total sample of 175 charts was obtained, whose extracted data were analyzed and plotted. Regarding distribution by gender, we found a major presence of female patients in attendance, corresponding to 63% of our sample. Thereafter, greater proportion of patients in the age group of 60 to 69 years was observed in both genres (25 females and 14 males). Considering an ethnic distribution, it was observed that majority of the patients of both genders declared themselves as white-skinned (52 females and 30 males). Among the most diagnosed lesions at the clinic, epithelial pathology was more frequent (n = 23), followed by soft tissue tumors (n = 18), developmental defects (n = 16), bone pathology (n = 14) and dermatological diseases (n = 11). Finally, the percentage of agreement between an initial and a final diagnostic was observed, and among the majorities of the diagnoses, there was a positive correlation (84%). Thus, in this work, the population attended at the clinic consisted, in the majority, of white women between the ages of 40 and 69, with fibrous hyperplasia as most frequent diagnosis. Finally, it is important to point out that the high agreement between an initial hypothesis and the final diagnosis is of utmost importance for excellence in oral medicine attendance, evidencing a quality of the service.

Keywords: Epidemiology; Oral medicine; Diagnosis; Oral..

Anaplastic Large Cell Lymphoma CD30+ ALK- in the Oral Cavity as a Primary Manifestation in HIV+ Patient: case report

Nicolás Leonardi1; Ricardo Christían Caciva1; Eduardo David Piemonte1; Martín Brusa1; Rubén Sambuelli2; Adrián Allende1; René Luis Panico1

Abstract Download

Anaplastic large cell lymphoma (ALCL) is a rare subtype of T-cell lymphoma that may involve mucocutaneous sites, in primary form, or secondary to systemic disease. It is a systemic malignancy characterized by an extranodal phenotype that rarely occurs in the oral cavity as the first manifestation of acquired immunodeficiency syndrome. In the primary forms, ALCL stands out for its favorable prognosis, being important to differentiate them clinically from the secondary ones, which have a rapid and aggressive evolution. For its diagnosis, it requires a rigorous physical and clinical examination and a duly oriented anatomopathological and immunohistochemical evaluation. In the present work, a clinical case of ALCL secondary to HIV is presented, detailing clinical characteristics, anatomopathological description, immunohistochemical profile and evolution against treatment.

Keywords: Lymphoma; HIV; Mouth, Neoplasms.

Review Article

Endodontic treatment in patients previously subjected to head and neck radiotherapy: a literature review

Wellington Hideaki Yanaguizawa1; Solange Kobayashi-Velasco1; Ivan Onone Gialain1; Celso Luiz Caldeira2; Marcelo Gusmao Paraiso Cavalcanti1

Abstract Download

The head and neck region is an expressive site of malignant neoplasms. Radiation therapy is a type of cancer treatment that can be used before or after surgical procedures, or in contraindicated surgery cases. Radiotherapy can cause various side effects in the patient's mouth, including xerostomia, mucositis, radiation cavities, and osteoradionecrosis. Due to the risk of osteoradionecrosis after dental extractions, endodontic treatment ends up being the best preventive and therapeutic method. The purpose of this study is to review the literature on endodontic treatment in cancer patients undergoing radiotherapy.

Keywords: Radiotherapy, Osteoradionecrosis, Endodontic treatment.

Is aloe vera effective for wound healing? The state of the art

Juliana Santos de Jesus Azevedo; Erielma Lomba Dias Juliao; Juliana Borges de Lima Dantas; Júlia Vianna Neri Andrade Reis

Abstract Download

INTRODUCTION:Aloe vera is a herbal plant that has been used widely for centuries as a natural medicine. Its therapeutic activity is based on the numerous beneficial pharmacological properties induced by the parenchyma. It is easy to access, manipulate and is low-cost; these properties have led to a progressive increase in its consumption. However, its action in the cicatricial process is not fully known, which has driven research into new discoveries in this context. AIM: The purpose of this literature narrative review was to discuss the current information available on the benefits of using Aloe vera in the wound healing process. MATERIALS AND METHODS: Scientific articles were selected from the Pub-Med and LILACS databases between February 2018 and July 2018, by using the English and Portuguese words of "Aloe Vera", "Wound healing", "Healing" and "Tissue repair". In total, 229 articles were found in PubMed and 63 articles were found in LILACS. After reading the abstracts, 30 articles that reported how the pharmacological properties of Aloe vera influence the healing process were selected. RESULTS:Aloe vera exerted positive effects on the treatment of oral ulcers and protection of the mucous membranes, with reductions in these lesions and the painful symptomatology. In addition, it was effective for the prevention and treatment of oral mucositis and the reduction of candidiasis in patients with cancer. Promising results have also been reported from the treatment of symptomatic oral lichen planus. In the treatment of plaque-induced gingivitis, Aloe vera provided a significant improvement in inflammation. FINAL CONSIDERATIONS: The literature supports the anti-inflammatory and cicatricial potential of Aloe vera, which has a wide indication for the treatment of several conditions. Therefore, additional clinical studies based on scientific evidence are needed to gain a better understanding of Aloe vera, its compounds and therapeutic indications.

Keywords: Aloe; Wound healing; Plants, medicinal.



© Copyright 2020 - Jordi - All rights reserved GN1