Calcifying odontogenic cyst treated by a two-stage surgical approach and reconstructed with L-PRF membrane associated to lyophilized bovine bone graft

Authors

  • Juliana Portes Universidade Federal Fluminense
  • Karin Soares Gonçalves Cunha Universidade Federal Fluminense
  • Bianca Bravim Universidade Federal Fluminense
  • Sérgio Gonçalves Universidade Federal Fluminense
  • Marina Urquiza Universidade do Estado do Rio de Janeiro
  • Danielle Castex Conde Universidade Federal Fluminense https://orcid.org/0000-0003-0038-8909

DOI:

https://doi.org/10.5935/2525-5711.20190007

Keywords:

Calcifying odontogenic cyst, Decompression, Bone regeneration

Abstract

Calcifying odontogenic cyst is an uncommon oral lesion, accounting for less than 1% of all odontogenic cysts. We report a case of a 28-year-old female with a complaint of a painless swelling on the anterior mandible area. Panoramic radiography and computed tomography showed a well-defined unilocular radiolucency with a radiopaque focal area, extending from the apical region of teeth 34 to 43. An incisional biopsy showed a cystic lesion lined by ameloblastoma-like epithelium with the presence of ghost cells and calci- fying material consistent with the diagnosis of calcifying odontogenic cyst. The treatment of choice was decompression with posterior enucleation of the lesion, and the region was filled-up with L-PRF membrane (Leukocyte – Platelet Rich Fibrin) and lyophilized bovine bone graft (Bio-Oss®). A two-stage treatment starting with decompression allows the prevention of some complications, such as fracture of the jaw or injury of noble structures and consequently, decreases the chances of recurrence. To the best of our knowledge, there are few published cases of COC treated by decompression followed by enucleation. The patient remains on follow-up and after 14 months, there is no sign of recurrence.

Author Biographies

Juliana Portes, Universidade Federal Fluminense

Patologia Oral

Karin Soares Gonçalves Cunha, Universidade Federal Fluminense

Patologia Oral

Bianca Bravim, Universidade Federal Fluminense

 Cirurgia e Traumatologia Bucomaxilofacial

Sérgio Gonçalves, Universidade Federal Fluminense

Cirurgia e Traumatologia Bucomaxilofacial

Marina Urquiza, Universidade do Estado do Rio de Janeiro

Residência em Cirurgia Bucomaxilofacial

Danielle Castex Conde, Universidade Federal Fluminense

Patologia Oral

References

El-Naggar AK, Chan JK, Grandis JR, Takata T, Slootweg PJ. WHO Classification of head and neck tumors. 4th Ed. Lyon: IARCPress, 2017.

Arruda JAA, Monteiro JLGC, Abreu LG, Silva LVO, Schuch LF, Noronha MS, Callou G, Moreno A, Mesquita RA. Calcifying odontogenic cyst, dentinogenic ghost cell tumor and ghost cell odontogenic carcinoma: a systematic review. J Oral Pathol Med. 2018; 1-10.

Desai RS, Sabnis R, Bhuta BA, Yadav A. Calcifying Cystic Odontogenic Tumor in a 5-Year-Old Boy: A Case Report. J Maxillofac Oral Surg. 2015; 14(1): 348-351.

Gadipelly S, Reddy VB, Sudheer M, Kumar NV e Harsha. Bilateral Calcifying Odontogenic Cyst: a rare entity. J Maxillofac Oral Surg. 2015; 14(3): 826-831.

Khandelwal P, Aditya A, Mhapuskar A. Bilateral Calcifying Cistic Odontogenic Tumor of Mandible: A Rare Case Report and Review of Literature. J Clin Diagn Res. 2015; 9(11): 20-22.

Radheshyam C, Alokenatj B, Kumar H, Abikshyeet. Calcifying cystic odontogenic tumor associated with odontome - a diverse lesion encountered. Clin Cosmet Investig Dent. 2015; 7: 91-95.

Medeiros PB, Avelar RL, Oliveira Neto PJ, Andrade ESS. Gorlin's cyst: a case report and literature review. Rev. Cir. Traumatol. Buco-Maxilo-Fac. 2007; 7(1): 59-64.

Souza NS, Souza ACRA, Gomes CC, Loyola AM, Durighetto AF, Gomez RS, Castro WH. Conservative treatment of calcifying odontogenic cyst: Report of 3 cases. J Oral Maxillofac Surg. 2007; 65: 2353-2356.

Speight P, Shear M. Cysts of the Oral and Maxillofacial Regions. 4th Ed. Oxford: Blackwell Munksgaard; 2007.

Utumi ER, Pedron IG, da Silva LP, Machado GG, Rocha AC. Distintas manifestaçoes do tumor odontogênico cístico calcificante. Einstein. 2012; 10(3): 366-370.

Rojo R, Prados-Frutos JC, Lázaro G, Alonso Herguedas JA. Calcifiyng odontogenic cysts. J Stomatol Oral Maxillofac Surg. 2017; 118: 122-124.

Emam HA, Smith J, Briody A, Jotana CA. Tube Decompression for Stage Treatment of Calcifying Odontogenic Cyst - A Case Report. J Oral Maxillofac Surg. 2017; 75(9): 1-6.

Sharma B, Koshy G, Kapoor S. Calcifying odontogenic cyst with luminal and mural component (Type 1c). Indian J Dent. 2016; 7(2): 95-98.

Kim Y, Choi BE, Ko S. Conservative approach to recurrent calcifying cystic odontogenic tumor occupying the maxillary sinus: a case report. J Korean Assoc Oral Maxillofac Surg. 2016; 42(5): 315-320.

Sheikh J, Cohen MD, Ramer N, Payami A. Ghost Cell Tumors. J Oral Maxillofac Surg. 2017; 75: 750-758.

Barnes L, Eveson JW, Reichart P, Sidransky D. Pathology and Genetics of Head and Neck Tumors.1st Ed. Lyon: IARCPress; 2005.

Neville BW, Damm DD, Allen CM, Chi AC. Oral and Maxillofacial Pathology. 4th Ed. Missouri: Elsevier; 2016.

Balaji SM and Rooban T. Calcigying odontogenic cyst with atypical features. Ann Maxillofac Surg; 2002; 2(1): 82-85.

Rahpeyma, A and Khajehahmadi S. Marsupialization for Treatment of Jaw Cysts: Indications and Limitations. J International Oral Health. 2016; 8(2): 158-162.

Gorlin RJ, Pindborg JJ, Clausen FP. The calcifying odontogenic cyst: a possible analogue of the cutaneous calcifying epithelioma of Malherbe. Oral Surg Oral Med Oral Pathol. 1962; 15: 1235. Apud Emam HA, Smith J, Briody A, Jotana CA. Tube Decompression for Stage Treatment of Calcifying Odontogenic Cyst - A Case Report. J Oral Maxillofac Surg. 2017; 75(9):1-6.

Kramer IR, Pindborg JJ, Shear M. World Health Organization International Histological Typing of Odontogenic Tumors. 2nd Ed. Berlin: Springer-Verlag Berlin Heidelberg; 1992.

Wright JM, Odell EW, Speight PM, Takata T. Odontogenic Tumors, WHO: Where do we go from here? Head and Neck Pathol. 2014; 8: 373-382.

Ledesma-Montes C, Gorlin RJ, Shear M, Praetorius F, Mosqueda-Taylor A, Altini M, Unni K, Paes de Almeida O, Carlos-Bregni R, Romero de Léon E, Phillips V, Delgado-Azañero W, Meneses-García A. International collaborative study on ghost cell odontogenic tumours: calcifying cystic odontogenic tumour, dentinogenic ghost cell tumour and ghost cell odontogenic carcinoma. J Oral Pathol Med. 2008; 37: 302-8.

Sarode GS, Sarode SC, Prajapati G, Maralingannavar M, Patil S. Calcifying Cystic Odontogenic Tumor in Radiologically Normal Dental Follicle Space of Mandibular Third Molars: Report of Two Cases. Clin Pract. 2017; 7(1): 933.

Downloads

Published

2019-01-15

How to Cite

1.
Portes J, Cunha KSG, Bravim B, Gonçalves S, Urquiza M, Conde DC. Calcifying odontogenic cyst treated by a two-stage surgical approach and reconstructed with L-PRF membrane associated to lyophilized bovine bone graft. J Oral Diagn [Internet]. 2019 Jan. 15 [cited 2024 Sep. 19];4:1-7. Available from: https://jordi.com.br/revista/article/view/121

Issue

Section

Case Report