Leiomyoma with intracytoplasmic inclusion bodies in the oral cavity
an uncommon histological finding
DOI:
https://doi.org/10.5935/2525-5711.20180020Keywords:
Leiomyoma, Inclusion Bodies, MouthAbstract
Leiomyomas are benign tumors that arise from the smooth musculature and can occur in any part of the body where these muscles are present. However, leiomyomas of the oral cavity are rare because of the scarcity of smooth muscles at this site. We present a case of leiomyoma involving the tongue which exhibited a histological finding that is extremely rare in oral leiomyomas. Immunohistochemical analysis revealed positivity for smooth muscle actin (alfa - SMA, desmin) and negativity for S - 100, CD- 68 and CD34 protein. The main clinical and histopathological features of leiomyomas, as well as their differential diagnosis, were reviewed. Intracytoplasmic inclusion bodies have been found in uterine leiomyomas, in atypical (bizarre) leiomyomas and, occasionally, in epithelioid leiomyomas and leiomyosarcomas. However, a search of the main literature databases revealed no description of these inclusions in oral leiomyomas.
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Copyright (c) 1969 Denise Hélen Imaculada Pereira de Oliveira, Marcelo Anderson Barbosa Nascimento, Lélia Maria Guedes Queiroz, Leão Pereira Pinto, Lélia Batista de Souza
This work is licensed under a Creative Commons Attribution 4.0 International License.
