Uncommon presentation of an intraosseous squamous cell carcinoma
DOI:
https://doi.org/10.5935/2525-5711.20180009Keywords:
Immunohistochemistry, Mouth Neoplasms, Carcinoma, Squamous CellAbstract
Primary intraosseous squamous cell carcinoma (PIOSCC) is a rare type of cancer, which commonly arises in the jaw without attachment to the oral mucosa epithelium and presumably develops from remnants of odontogenic epithelium or from odontogenic cysts and odontogenic benign tumors. We report here a case of a 49-year-old male patient who presented pain in the teeth 44 and 45 region. Radiographic examination revealed a small radiolucent and well circumscribed lesion, however, histopathological examination revealed a PISCC. The clinical and radiographic presentation of this tumor can be variable and nonspecific, and even small osteolytic lesions in the gnathic bones can be considered as differential diagnosis of malignant neoplasms of odontogenic origin. Incisional biopsy is fundamental to lead to early diagnosis and indicate appropriate treatment to optimize the prognosis of these cases.
References
Wenguang X, Hao S, Xiaofeng Q, Zhiyong W, Yufeng W, Qingang H, et al. Prognostic Factors of Primary Intraosseous Squamous Cell Carcinoma (PIOSCC): A Retrospective Review. PLoS One. 2016;11:e0153646.
Bodner L, Manor E, Shear M, van der Waal I. Primary intraosseous squamous cell carcinoma arising in an odontogenic cyst: a clinicopathologic analysis of 116 reported cases. J Oral Pathol Med. 2011;40:733-8.
Boni P, Sozzi D, Novelli G, Pagni F, Valente G, Bozzetti A. Primary Intraosseous Squamous Cell Carcinoma of the Jaws: 6 New Cases, Experience, and Literature Comparison. J Oral Maxillofac Surg. 2016;74:541-6.
Wright JM, Vered M. Update from the 4th Edition of the World Health Organization Classification of Head and Neck Tumours: Odontogenic and Maxillofacial Bone Tumors. Head Neck Pathol. 2017;11:68-77.
Suei Y, Tanimoto K, Taguchi A, Wada T. Primary intraosseous carcinoma: review of the literature and diagnostic criteria. J Oral Maxillofac Surg. 1994;52:580-3.
Naruse T, Yanamoto S, Sakamoto Y, Ikeda T, Yamada SI, Umeda M. Clinicopathological Study of Primary Intraosseous Squamous Cell Carcinoma of the Jaw and a Review of the Literature. J Oral Maxillofac Surg 2016;74:2420-7.
Jain M, Mittal S, Gupta DK. Primary intraosseous squamous cell carcinoma arising in odontogenic cysts: an insight in pathogenesis. J Oral Maxillofac Surg. 2013;71:e7 14.
Grisar K, Schol M, Hauben E, Schoenaers J, Politis C. Primary intraosseous squamous cell carcinoma of the mandible arising from an infected odontogenic cyst: A case report and review of the literature. Oncol Lett. 2016;12:5327-31.
Tamgadge S, Tamgadge A, Modak N, Bhalerao S. Primary intraosseous squamous cell carcinoma arising from an odontogenic keratocyst: a case report and literature review. Ecancermedicalscience. 2013;7:316.
Kamath KP, Vidya M. Cytokeratin 19 expression patterns of dentigerous cysts and odontogenic keratocysts. Ann Med Health Sci Res. 2015;5:119-23.
Chaisuparat R, Coletti D, Kolokythas A, Ord RA, Nikitakis NG. Primary intraosseous odontogenic carcinoma arising in an odontogenic cyst or de novo: a clinicopathologic study of six new cases. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2006;101:194-200.
Martínez-Martínez M, Mosqueda-Taylor A, Delgado-Azañero W, Rumayor-Piña A, de Almeida OP. Primary intraosseous squamous cell carcinoma arising in an odontogenic keratocyst previously treated with marsupialization: case report and immunohistochemical study. Oral Surg Oral Med Oral Pathol Oral Radiol. 2016;121:e87-95.
Alotaibi O, Al-Zaher N, Alotaibi F, Khoja H, Qannam A. Solid-type primary intraosseous squamous-cell carcinoma in the mandible: Report of a rare case. Hematol Oncol Stem Cell Ther. 2016;9:118-22.
Iino M, Ishikawa S, Ozaki H, Kobayashi T, Tachibana H, Sakurai H, et al. Solid type primary intraosseous squamous cell carcinoma in the maxilla: report of a new case. BMC Ear Nose Throat Disord. 2013;13:13.
Choi YJ, Oh SH, Kang JH, Choi HY, Kim GT, Yu JJ, et al. Primary intraosseous squamous cell carcinoma mimicking periapical disease: a case report. Imaging Sci Dent. 2012;42:265-70.
Matsuzaki H, Katase N, Matsumura T, Hara M, Yanagi Y, Nagatsuka H, et al. Solid-type primary intraosseous squamous cell carcinoma of the mandible: a case report with histopathological and imaging features. Oral Surg Oral Med Oral Pathol Oral Radiol. 2012;114:e71-7.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 1969 Leorik Pereira da-Silva, Amanda Katarinny Goes Gonzaga, Luciana Eloisa da Silva Castro-Nóbrega, Adriano Rocha Germano, Antonio de Lisboa Lopes Costa
This work is licensed under a Creative Commons Attribution 4.0 International License.
