Critical appraisal of determinant factors of an extensive oral squamous cell carcinoma - Report of case

Authors

  • Natália Batista Daroit Universidade Federal do Rio Grande do Sul. Faculdade Sao Leopoldo Mandic https://orcid.org/0000-0002-0764-8999
  • Monique Santanna Candreva Faculdade São Leopoldo Mandic
  • Nathália de Almeida Freire Faculdade São Leopoldo Mandic
  • Sarah Aparecida Ferreira Antero Faculdade São Leopoldo Mandic
  • Pantelis Varvaki Rados Federal University of Rio Grande do Sul
  • Mônica Simoes Israel Faculdade São Leopoldo Mandic https://orcid.org/0000-0002-9234-7903

DOI:

https://doi.org/10.5935/2525-5711.20180013

Keywords:

Mouth Neoplasms, Risk Factors, Diagnosis

Abstract

Introduction: Oral squamous cell carcinoma (OSCC) is the most frequently occurring oral malignant neoplasm. Early diagnosis is essential for determining the treatment and prognosis of OSCC. Objective: The aim of this study was to report a case of an extensive OSCC, to discuss factors involved in the diagnosis of advanced lesions and to clarify diffi- culties experienced in referring patients with OSCC for treatment to a healthcare system. Methods: The study included male patients aged 50 years who were chronic alcoholic and tobacco smokers, who had severe trismus, and who presented with ulceroprolifera- tive growth with indurated raised margins, involving the left palate and lower gingiva, extending into the buccal mucosa, and overlying the skin. Results: An incisional biopsy confirmed the diagnosis of OSCC, and the patient was referred for treatment. Conclusions: The factors that delay the diagnosis of OSCCs are misinformation, self-care negligence, socioeconomic aspects, inappropriate oral mucosa examinations, unknown oral diseases, and failure to obtain a conclusive diagnosis and forwarding the patient to the treatment.

Author Biographies

Natália Batista Daroit, Universidade Federal do Rio Grande do Sul. Faculdade Sao Leopoldo Mandic

Universidade Federal do Rio Grande do Sul - UFRGS, Dental School, Department of Conservative Dentistry. Faculdade Sao Leopoldo Mandic, Stomatology Specialization.

Monique Santanna Candreva, Faculdade São Leopoldo Mandic

Stomatology Specialization

Nathália de Almeida Freire, Faculdade São Leopoldo Mandic

Stomatology Specialization

Sarah Aparecida Ferreira Antero, Faculdade São Leopoldo Mandic

Stomatology Specialization

Pantelis Varvaki Rados, Federal University of Rio Grande do Sul

Dental School, Department of Conservative Dentistry

Mônica Simoes Israel, Faculdade São Leopoldo Mandic

Stomatology Specialization

References

Chang JH, Wu CC, Yuan KS, Wu ATH, Wu SY. Locoregionally recurrent head and neck squamous cell carcinoma: incidence, survival, prognostic factors, and treatment outcomes. Oncotarget. 2017;8:55600-12.

Carreras-Torras C, Gay-Escoda C. Techniques for early diagnosis of oral squamous cell carcinoma: Systematic review. Med Oral Patol Oral Cir Bucal. 2015;20:e305-15.

Petti S. Lifestyle risk factors for oral cancer. Oral Oncol. 2009;45:340-50.

Brazil. Health Ministry. Instituto Nacional de Câncer (INCA). Estimativa do Câncer de Boca para o ano de 2018. [Internet]. Brasília: Ministério da Saúde; 2018. [cited 2018 May 16]. Available from: http://www2.inca.gov.br/wps/wcm/connect/tiposdecancer/site/home/boca/definicao

Hammerlid E, Bjordal K, Ahlner-Elmqvist M, Boysen M, Evensen JF, Biörklund A, et al. A prospective study of quality of life in head and neck cancer patients. Part I: at diagnosis. Laryngoscope. 2001;111(4 Pt 1):1-12.

Pitiphat W, Diehl SR, Laskaris G, Cartsos V, Douglass CW, Zavras AI. Factors associated with delay in the diagnosis of oral cancer. J Dent Res. 2002;81:192-7.

Greenwood M, Thomson PJ, Lowry RJ, Steen IN. Oral cancer: material deprivation, unemployment and risk factor behaviour--an initial study. Int J Oral Maxillofac Surg. 2003;32:74-7.

Marur S, Forastiere AA. Head and neck cancer: changing epidemiology, diagnosis, and treatment. Mayo Clin Proc. 2008;83:489-501.

Meyer MS, Joshipura K, Giovannucci E, Michaud DS. A review of the relationship between tooth loss, periodontal disease, and cancer. Cancer Causes Control. 2008;19:895-907.

El-Naggar AK, Chan JKC, Grandis JR, Takata T, Slootweg PJ. Malignant Surface Epithelial Tumors. In: WHO Classification of Head and Neck Tumours. 4th ed. Lyon: IARC Press; 2017. p. 109-11.

Rajeev R, Choudhary K, Panda S, Gandhi N. Role of bacteria in oral carcinogenesis. South Asian J Cancer. 2012;1:78-83.

da Silva MC, Marques EB, Melo LC, Bernardo JMP, Leite ICG. Associated Factors for the Delay in the Diagnosis of Oral and Oropharynx Cancer in Juiz de Fora/MG. Rev Bras Cancerol. 2009;55:329-35.

Panzarella V, Pizzo G, Calvino F, Compilato D, Colella G, Campisi G. Diagnostic delay in oral squamous cell carcinoma: the role of cognitive and psychological variables. Int J Oral Sci. 2014;6:39-45.

Andrade JO, Santos CA, Oliveira MC. Associated factors with oral cancer: a study of case control in a population of the Brazil's Northeast. Rev Bras Epidemiol. 2015;18:894-905.

Miller GE, Pylypchuk Y. Marital Status, Spousal Characteristics, and the Use of Preventive Care. J Fam Econ Issues. 2014;35:323-38.

Averett S, Argys LM, Sorkin J. In sickness and in health: an examination of relationship status and health using data from the Canadian National Public Health Survey. Rev Econ Househ. 2012;11:599-633.

Zhang H, Dziegielewski PT, Jean Nguyen TT, Jeffery CC, O'Connell DA, Harris JR, et al. The effects of geography on survival in patients with oral cavity squamous cell carcinoma. Oral Oncol. 2015;51:578-85.

Spalthoff S, Holtmann H, Krüskemper G, Zimmerer R, Handschel J, Gellrich NC, et al. Regular Dental Visits: Influence on Health-Related Quality of Life in 1,607 Patients with Oral Squamous Cell Carcinoma. Int J Dent. 2017;2017:9638345.

Traebert E, Traebert J. Oral cancer in Brazil: dentists' lack of technical knowledge. Braz Oral Res. 2015;29. pii: S1806-83242015000100500.

Awojobi O, Newton JT, Scott SE. Why don't dentists talk to patients about oral cancer? Br Dent J. 2015;218:537-41.

Joseph BK, Sundaram DB, Ellepola AN. Assessing Oral Cancer Knowledge Among Undergraduate Dental Students in Kuwait University. J Cancer Educ. 2015;30:415-20.

Leao JC, Góes P, Sobrinho CB, Porter S. Knowledge and clinical expertise regarding oral cancer among Brazilian dentists. Int J Oral Maxillofac Surg. 2005;34:436-9.

Gao W, Guo CB. Factors related to delay in diagnosis of oral squamous cell carcinoma. J Oral Maxillofac Surg. 2009;67:1015-20.

Stefanuto P, Doucet JC, Robertson C. Delays in treatment of oral cancer: a review of the current literature. Oral Surg Oral Med Oral Pathol Oral Radiol. 2014;117:424-9.

Abdo EN, Garrocho Ade A, Barbosa AA, Oliveira EL, Franca-Filho L, Negri SL, et al. Time elapsed between the first symptoms, diagnosis and treatment of oral cancer patients in Belo Horizonte, Brazil. Med Oral Patol Oral Cir Bucal. 2007;12:E469-73.

Lombardo EM, da Cunha AR, Carrard VC, Bavaresco CS. Delayed referrals of oral cancer patients: the perception of dental surgeons. Cienc Saude Colet. 2014;19:1223-32.

Downloads

Published

2018-01-20

How to Cite

1.
Daroit NB, Candreva MS, Freire N de A, Antero SAF, Rados PV, Israel MS. Critical appraisal of determinant factors of an extensive oral squamous cell carcinoma - Report of case. J Oral Diagn [Internet]. 2018 Jan. 20 [cited 2024 Sep. 19];3:1-5. Available from: https://jordi.com.br/revista/article/view/167

Issue

Section

Case Report