Medication-Related Osteonecrosis of the Jaw Treated by Ozonized Oil
A Case Report
Keywords:
Medication-related osteonecrosis of the jaw, Ozone therapy, AlendronateAbstract
Ozone is an atmospheric gas well-known for its excellent medicinal properties, including antimicrobial activity, immunostimulant and antioxidative. Ozone therapy has been used in dental medicine for treatment of herpetic infection, periodontitis, endodontic infec- tion, acute abscesses and medication-related osteonecrosis of the jaw. This study aims to report the protocol and results of the local use of ozonized oil in the management of patient with medication-related osteonecrosis of the jaw. 81-year-old white female, with exposed bone in the jaw, on left side, and a history of sodium alendronate used to treat osteoporosis. The treatment consisted of ozone therapy with ozonized oil, according to the following protocol: previous mouthwash chlorhexidine 0.12%, Periogard®, for one minute; local application of ozonized oil, Philozon®, with a 5ml syringe no needle, for 10 minutes, re-appliance every two minutes; 10 sessions, once a week each. Between the eighth and ninth treatment week, we observed spontaneous bone sequestration and after six months of follow up, we found local tissue regeneration.
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Copyright (c) 1969 Mariana Pinheiro Saldanha, Beatriz Fernandes de-Moura, Renata Ximenes Lins, Beatriz da Rocha Miranda Venturi, Nathalia de Almeida Freire, Mônica Simões Israel
This work is licensed under a Creative Commons Attribution 4.0 International License.
