A rare case of oral metastasis of renal clear cell carcinoma

case report and review of literature

Authors

  • Luan Nathiel Santana Kovalski Universidade Federal do Rio Grande do Sul https://orcid.org/0000-0002-0426-3110
  • Julia Turra Ribeiro Universidade Federal do Rio Grande do Sul
  • Manoela Domingues Martins Universidade Federal do Rio Grande do Sul. Hospital de Clínicas de Porto Alegre
  • Marcia Gaiger De Oliveira Universidade Federal do Rio Grande do Sul
  • Luis Fernando Rivero Hospital de Clinicas de Porto Alegre
  • Vinicius Coelho Carrard Universidade Federal do Rio Grande do Sul. Hospital de Clínicas de Porto Alegre
  • Marco Antonio Trevizani Martins Universidade Federal do Rio Grande do Sul. Hospital de Clínicas de Porto Alegre

DOI:

https://doi.org/10.5935/2525-5711.20200006

Keywords:

Oral Manifestatios, Carcinoma, Renal Cell, Gingiva

Abstract

This is a case report of metastasis of renal clear cell carcinoma, a very rare malignant neoplasia, in the oral cavity. The patient went to the oral medicine clinic complaining of a nodule in the left upper gingival region that had started a month previously. Clinical evaluation revealed a large, red and bleeding nodule in the superior gingiva of the left side of the maxilla. A panoramic radiographic revealed alveolar bone destruction. Incisional biopsy was performed, and microscopic evaluation revealed an unspecified malignant neo- plasia. The patient was referred to a local hospital for investigation. A systemic evaluation showed a large nodule in the right kidney, another nodule in the liver, small nodules in both lungs and two nodules in the brain. A biopsy of the right kidney was performed, showing a renal clear cell carcinoma. After that, new immunohistochemical analysis of the oral lesion was performed demonstrating it to be one more implant of renal neopla- sia. The final diagnosis was renal clear cell carcinoma, with metastases in the liver, lung, mouth and nervous system. Unfortunately, the patient died six months after the diagnosis. The primary tumour was only discovered due to the oral manifestation of the disease, emphasising the importance of oral medicine in the diagnosis of metastatic lesions.

Author Biographies

Luan Nathiel Santana Kovalski, Universidade Federal do Rio Grande do Sul

Oral Medicine and Oral Pathology Department

Julia Turra Ribeiro, Universidade Federal do Rio Grande do Sul

Oral Medicine and Oral Pathology Department

Manoela Domingues Martins, Universidade Federal do Rio Grande do Sul. Hospital de Clínicas de Porto Alegre

Universidade Federal do Rio Grande do Sul, Oral Medicine and Oral Pathology Department.  Hospital de Clínicas de Porto Alegre, Oral Medicine Department

Marcia Gaiger De Oliveira, Universidade Federal do Rio Grande do Sul

Oral Medicine and Oral Pathology Department

Luis Fernando Rivero, Hospital de Clinicas de Porto Alegre

Pathology Department

Vinicius Coelho Carrard, Universidade Federal do Rio Grande do Sul. Hospital de Clínicas de Porto Alegre

Universidade Federal do Rio Grande do Sul, Oral Medicine and Oral Pathology Department. Hospital de Clínicas de Porto Alegre, Oral Medicine Department

Marco Antonio Trevizani Martins, Universidade Federal do Rio Grande do Sul. Hospital de Clínicas de Porto Alegre

Universidade Federal do Rio Grande do Sul, Oral Medicine and Oral Pathology Department. Hospital de Clínicas de Porto Alegre, Oral Medicine Department

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Published

2020-01-11

How to Cite

1.
Kovalski LNS, Ribeiro JT, Martins MD, Oliveira MGD, Rivero LF, Carrard VC, et al. A rare case of oral metastasis of renal clear cell carcinoma: case report and review of literature. J Oral Diagn [Internet]. 2020 Jan. 11 [cited 2024 Sep. 19];5:1-9. Available from: https://jordi.com.br/revista/article/view/74

Issue

Vol. 5 (2020)

Section

Case Report

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Copyright (c) 1969 Luan Nathiel Santana Kovalski, Julia Turra Ribeiro, Manoela Domingues Martins, Marcia Gaiger De Oliveira, Luis Fernando Rivero, Vinicius Coelho Carrard, Marco Antonio Trevizani Martins

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This work is licensed under a Creative Commons Attribution 4.0 International License.