Conservative approach in the odontogenic myxoma treatment: an alternative with less morbidity
DOI:
https://doi.org/10.5327/2525-5711.425Keywords:
Odontogenic myxoma, Odontogenic tumor, Conservative treatmentAbstract
A 21 year-old female patient treated in the Maxillofacial Surgery Unit of Dr. Sotero del Rio Hospital, with a mandibular Odontogenic Myxoma diagnosis. Related to this clinical case and its aspects, is why we propose a more conservative alternative of treatment than mandibular segmental resection with safety margins. Through post surgical clinical and imaging surveillance, we can establish that using a conservative treatment for Odontogenic Myxoma with less local aggressiveness features, we can obtain favorable results in the long term and far less morbidity for the patient.
References
Vered M, Wright JM. Update from the 5th Edition of the World Health Organization Classification of head and neck tumors: odontogenic and maxillofacial bone tumours. Head Neck Pathol. 2022;16(1):63-75. https://doi.org/10.1007/s12105-021-01404-7
Gomes CC, Diniz MG, Duarte AP, Bernardes VF, Gomez RS. Molecular review of odontogenic myxoma. Oral Oncol. 2011;47(5):325-8. https://doi.org/10.1016/j.oraloncology.2011.03.006
Chrcanovic BR, Gomez RS. Odontogenic myxoma: an updated analysis of 1,692 cases reported in the literature. Oral Dis. 2019;25(3):676-83. https://doi.org/10.1111/odi.12875
Shivashankara C, Nidoni M, Patil S, Shashikala KT. Odontogenic myxoma: a review with report of an uncommon case with recurrence in the mandible of a teenage male. Saudi Dent J. 2017;29(3):93-101. https://doi.org/10.1016/j.sdentj.2017.02.003
Gupta S, Grover N, Kadam A, Gupta S, Sah K, Sunitha J. Odontogenic myxoma. Natl J Maxillofac Surg. 2013;4(1):81-3. https://doi.org/10.4103/0975-5950.117879
Boffano P, Stathopoulos P, Ruslin M. Pathological and molecular features of odontogenic myxoma: a systematic review. Indian J Otolaryngol Head Neck Surg. 2025;77(7):2711-8. https://doi.org/10.1007/s12070-025-05552-y
Ortiz AFH, Almarie B, Murcia ND, Farhane MA. Odontogenic myxoma: a case report of a rare tumor. Radiol Case Rep. 2023;18(11):4130-3. https://doi.org/10.1016/j.radcr.2023.08.080
Perdigão PF, Stergiopoulos SG, De Marco L, Matyakhina L, Boikos SA, Gomez RS, et al. Molecular and immunohistochemical investigation of protein kinase a regulatory subunit type 1A (PRKAR1A) in odontogenic myxomas. Genes Chromosomes Cancer. 2005;44(2):204-11. https://doi.org/10.1002/gcc.20232
Dotta JH, Miotto LN, Spin-Neto R, Ferrisse TM. Odontogenic myxoma: systematic review and bias analysis. Eur J Clin Invest. 2020;50(4):e13214. https://doi.org/10.1111/eci.13214
Kumar N, Kohli M, Pandey S, Agarwal P. Odontogenic myxoma. J Maxillofac Oral Surg. 2010;13(2):222-6. https://doi.org/10.1007/s12663-010-0107-7
Trode H, Pouget C, Talbi M, Simon E, Brix M. Surgical management of odontogenic myxomas: a case series. Int J Surg Case Rep. 2023;112:108945. https://doi.org/10.1016/j.ijscr.2023.108945
Kawase-Koga Y, Saijo H, Hoshi K, Takato T, Mori Y. Surgical management of odontogenic myxoma: a case report and review of the literature. BMC Res Notes. 2014;7:214. https://doi.org/10.1186/1756-0500-7-214
Zanetti LSS, Carvalho BMH, Garcia Jr IR, de Barros LAP, Santos PL, Ferreira ACRM. Conservative treatment of odontogenic myxoma. J Craniofac Surg. 2011;22(5):1939-41. https://doi.org/10.1097/SCS.0b013e318211519e
Martins HDD, Vieira EL, Gondim ALMF, Osório-Júnior HA, Silva JSP, Silveira EJD. Odontogenic myxoma: follow-up of 13 cases after conservative surgical treatment and review of the literature. J Clin Exp Dent. 2021;13(7):e637-41. https://doi.org/10.4317/jced.58080
Saalim M, Sansare K, Karjodkar FR, Farman AG, Goyal SN, Sharma SR. Recurrence rate of odontogenic myxoma after different treatments: a systematic review. Br J Oral Maxillofac Surg. 2019;57(10):985-91. https://doi.org/10.1016/J.BJOMS.2019.09.005
Rocha AC, Gaujac C, Ceccheti MM, Amato-Filho G, Machado GG. Treatment of recurrent mandibular myxoma by curettage and cryotherapy after thirty years. Clinics (Sao Paulo). 2009;64(2):149-52. https://doi.org/10.1590/S1807-59322009000200013
Fariña-Sirandoni R, Núñez-Castañeda L, Donoso MA, Deramond-Díaz JP. Ethanol ablation for odontogenic myxoma: new alternative of conservative treatment. Int J Interdiscip Dent. 2023;16(1):85-7. http://dx.doi.org/10.4067/S2452-55882023000100085
Published
How to Cite
Issue
Section
License
Copyright (c) 2026 Cristian Lopez, Diego Ramírez Villalobos, Frobel Delgado Bedoya, Verónica Palacios Inostroza, Carola Caamaño Martínez

This work is licensed under a Creative Commons Attribution 4.0 International License.









