A Novel Case Report of CD5-Negative Mantle Cell Lymphoma Presenting in the Oral Cavity

Madison E. Richards; Scarlet Charmelo-Silva; Allison Buchanan; Natasha M. Savage; Rafik A. Abdelsayed

doi:10.5327/2525-5711.490

Authors

Madison E. Richards The Dental College of Georgia at Augusta University https://orcid.org/0009-0007-1874-7742
Scarlet Charmelo-Silva The Dental College of Georgia at Augusta University https://orcid.org/0009-0006-8132-3937
Allison Buchanan The Dental College of Georgia at Augusta University https://orcid.org/0009-0001-7444-4590
Natasha M. Savage Medical College of Georgia at Augusta University https://orcid.org/0000-0003-1474-9568
Rafik A. Abdelsayed The Dental College of Georgia at Augusta University https://orcid.org/0009-0008-4098-2391

DOI:

https://doi.org/10.5327/2525-5711.490

Keywords:

Mantle Cell Lymphoma, Mouth Neoplasms, Head and Neck Cancer, Diagnostic Imaging, Immunohistochemistry

Abstract

Proliferating lymphoid cells in lymphoma have the potential to involve not only lymph nodes, but other lymphoid tissues (including those in the oral cavity). This case represents a very rare diagnostic entity: oral extranodal presentation of CD5-negative Mantle cell lymphoma. In asymptomatic palatal swellings in adults, this uncommon variant of lymphoma should be considered in the differential diagnosis because early detection and treatment improve patient outcomes.

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