Idiopathic Bilateral Central Giant Cell Granuloma of Jaw- A Case Report and Brief Review of Reported Cases

Autores

  • Aarfa Nasim Subharti Dental College, Meerut, India
  • Ravi Prakash Sasankoti Mohan Subharti Dental College, Meerut, India
  • Nagaraju Kamarthi Subharti Dental College, Meerut, India
  • Vijay Wadhwan Subharti Dental College, Meerut, India

DOI:

https://doi.org/10.5935/2525-5711.20170005

Palavras-chave:

Giant Cells, Granuloma, Hyperparathyroidism, Mandible

Resumo

Central giant cell granuloma (CGCG) is a benign intraosseous reactive lesion of jaw with diverse clinical and radiological behaviour pattern. It accounts for 7% of neoplastic bone lesion of jaw with 70% occurring in mandible. CGCG was first considered as giant cell tumor mostly found in epiphyseal region of long bone having both aggressive and non- -aggressive pattern. The etiology of the lesion is not defined. Multiple CGCGs of the jaw bones is very rare and, if it occurs, it is usually associated with hyperparathyroidism in majority of the cases. We report an interesting case in which a 33 year old female came with a swelling present on right side of mandible which was asymptomatic. Another swelling was present on left side which was non-evident and asymptomatic. Clinical, radiological and histopathological examination confirmed the lesions as central giant cell granuloma. Biochemical examination showed no signs of hyperparathyroidism. This report represents a very rare entity in which there is idiopathic bilateral CGCG having both aggressive and non-aggressive type of lesion.

Referências

Jaffe HL. Giant cell reparative granuloma, traumatic bone cyst and fibrous (fibro-osseous) dysplasia of the jawbones. Oral Surg Oral Med Oral Pathol. 1953;6:159-75.

Kaur M, Singh J, Saxena S. Central Giant Cell Granuloma of Maxilla: A Case Report And Literature Review. Int J Clinic Dent Sci. 2012;3:82-6.

World Health Organization/International Agency for Research on Cancer; Barnes L, Eveson JW, Reichart P, Sidransky D, eds. Pathology and Genetics - Head and Neck Tumours. Lyon: lARC Press; 2005.

Whitaker SB, Bouquot JE. Estrogen and progesterone receptor status of central giant cell lesions of the jaws. Oral Surg Oral Med Oral Pathol. 1994;77:641-4.

Ustündağ E, Iseri M, Keskin G, Müezzinoğlu B. Central giant cell granuloma. Int J Pediatr Otorhinolaryngol. 2002;65:143-6.

Cohen MA, Hertzanu Y. Radiologic features, including those seen with computed tomography, of central giant cell granuloma of the jaws. Oral Surg Oral Med Oral Pathol. 1988;65:255-61.

Whitaker SB, Waldron CA. Central giant cell lesions of the jaws. A clinical, radiologic, and histopathologic study. Oral Surg Oral Med Oral Pathol. 1993;75:199-208.

Chuong R, Kaban LB, Kozakewich H, Perez-Atayde A. Central giant cell lesions of the jaws: a clinicopathologic study. J Oral Maxillofac Surg. 1986;44:708-13.

Ficarra G, Kaban LB, Hansen LS. Central giant cell lesions of the mandible and maxilla: a clinicopathologic and cytometric study. Oral Surg Oral Med Oral Pathol. 1987;64:44-9.

Rosai J. Ackerman's Surgical Pathology. Volume 1. 8th ed. St. Louis: CV Mosby; 1996. p. 259-60.

Triantafillidou K, Venetis G, Karakinaris G, Iordanidis F. Central giant cell granuloma of the jaws: a clinical study of 17 cases and a review of the literature. Ann Otol Rhinol Laryngol. 2011;120:167-74.

Reichart PA, Philipsen HP. Odontogenic Tumors and Allied Lesions. London: Quintessence Publishing; 2004. p. 319-30.

Liu B, Yu SF, Li TJ. Multinucleated giant cells in various forms of giant cell containing lesions of the jaws express features of osteoclasts. J Oral Pathol Med. 2003;32:367-75.

Hongal BP, Joshi P, Kulkarni V, Baldawa P. Central giant cell granulomas of the jaws: A Review Of The Literature With Its Emphasis On Differential Diagnosis On Related Lesions. Int J Contemp Dent Med Rev. 2015;010115.

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Publicado

2017-01-05

Como Citar

1.
Nasim A, Mohan RPS, Kamarthi N, Wadhwan V. Idiopathic Bilateral Central Giant Cell Granuloma of Jaw- A Case Report and Brief Review of Reported Cases. J Oral Diagn [Internet]. 5º de janeiro de 2017 [citado 19º de setembro de 2024];2:1-8. Disponível em: https://jordi.com.br/revista/article/view/176

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