Knowledge of Bisphosphonate and Medication-Related Osteonecrosis of the Jaw (MRONJ) among dentists in Southeastern Brazil: a cross-sectional study

Cynthia Moreira Miranda; Carla Reis Machado; Carla Silva Siqueira; Sérgio Vitorino Cardoso; Mirna Scalon Cordeiro; Marcelo Caetano Parreira da Silva; Marcelo Caetano Parreira da Silva

doi:10.5327/2525-5711.427

Autores

Cynthia Moreira Miranda Federal University of Uberlândia – Uberlândia (MG), Brazil. https://orcid.org/0009-0006-4792-160X
Carla Reis Machado Federal University of Uberlândia – Uberlândia (MG), Brazil. https://orcid.org/0000-0002-1659-8882
Carla Silva Siqueira Federal University of Uberlândia – Uberlândia (MG), Brazil. https://orcid.org/0000-0002-8749-2284
Sérgio Vitorino Cardoso Federal University of Uberlândia – Uberlândia (MG), Brazil. https://orcid.org/0000-0003-1809-0617
Mirna Scalon Cordeiro Federal University of Uberlândia – Uberlândia (MG), Brazil. https://orcid.org/0009-0008-6739-1823
Marcelo Caetano Parreira da Silva Federal University of Uberlândia – Uberlândia (MG), Brazil. https://orcid.org/0000-0001-6010-8062
Marcelo Caetano Parreira da Silva

DOI:

https://doi.org/10.5327/2525-5711.427

Palavras-chave:

Bisphosphonates, Osteonecrosis, Medication-related osteonecrosis, Oral surgery, Clinical Management

Resumo

Objective: This study aimed to evaluate the level of knowledge among dentists in Minas Gerais, Brazil, regarding bisphosphonates and their association with MRONJ, with emphasis on risk perception, preventive measures, and diagnostic awareness. Methods: This was a descriptive, cross-sectional, and quantitative study approved by the Research Ethics Committee of the Federal University of Uberlândia (protocol no. 6.135.292). A total of 95 dentists registered with the Regional Council of Dentistry participated by completing a structured online questionnaire. Results: While 69.5% of respondents reported knowing what bisphosphonates are, 83.2% recognized the risks of MRONJ in oral surgical procedures, and 87.4% were aware of the high likelihood of osteonecrosis in patients using these drugs. However, only 47.4% reported knowledge of preventive strategies, and 50.5% were familiar with clinical signs and symptoms used for diagnosis. Conclusions: Although dentists demonstrated general awareness of bisphosphonate-related osteonecrosis, significant knowledge gaps remain regarding its prevention and diagnostic criteria. These findings underscore the need for enhanced continuing education and training in evidence-based protocols to improve clinical outcomes and reduce complications associated with antiresorptive therapy in dental practice.

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